When IV access is unavailable, what is the typical glucagon dose for adults?

• A. 0.5 mg IM
• B. 1 mg IM
• C. 1.5 mg IM
• D. 2 mg IM

Answer: (B)

When IV access isn’t available, giving glucagon by intramuscular injection is the standard way to treat hypoglycemia in adults. Glucagon prompts the liver to release stored glucose (glycogenolysis), raising blood glucose quickly. The usual adult IM dose is 1 mg, chosen because it reliably produces a rapid glucose rise with a manageable risk of side effects. Smaller doses (like 0.5 mg) are used for smaller patients or children, while larger doses (1.5 mg or 2 mg) aren’t the standard initial dose for adults and aren’t typically needed. If there's no adequate response within about 10–15 minutes, seek IV access and administer additional glucose as appropriate.